It appears that horsepox not cowpox may have bern main ingrediant in smallpox vaccine. See:  Seeking the secret ingredient in the original smallpox vaccine — ScienceDaily

https://www.sciencedaily.com/releases/2017/08/170819103656.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fvaccines+%28Vaccines+News+–+ScienceDaily%29

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