Internasal Herpes Vaccine

A company called Blue Willow Biologicals recently received a patent for a novel Herpes Simplex 1 and 2 vaccine that both protects and has mherapuetic value. This is an exciting development as protection from Herpes Simplex and a therapuetic vaccine have proved elusive. I have reprinted the press release below:

BlueWillow Biologics Awarded Patent for Intranasal Genital Herpes Vaccine

accine Expected to Deliver Therapeutic and Preventive Protection

ANN ARBOR, Mich., (July 23, 2019) – BlueWillow Biologics® today announced the issuance of U.S. patent number 10,206,996 to BlueWillow for the development of an intranasal NanoVax® herpes simplex virus (HSV) vaccine. The patent protects the use of BlueWillow’s unique NanoVax adjuvant platform in the development of a vaccine that provides protection against HSV-1 and HSV-2, the two viruses that can cause genital herpes.

More than one in six people aged 14–49 are infected with genital herpes and an estimated 776,000 new infections occur annually, according to the Centers for Disease Control and Prevention (CDC). Genital herpes increases a person’s risk of contracting HIV and can lead to miscarriage and premature birth in infected pregnant women. Herpes can also be passed from the mother to child during birth, potentially resulting in neonatal herpes, a fatal infection. Most genital herpes vaccine candidates have failed or been abandoned in recent years, leaving no reliable therapeutic or preventive vaccine for the disease.

BlueWillow’s intranasal NanoVax platform elicits both mucosal and systemic immunity through its novel oil-in-water nanoemulsion (NE) adjuvant, offering a unique advantage to combat sexually transmitted infections (STIs) including genital herpes. The mucosal immunity elicited by intranasal NE vaccines provides critical protection against infections at the port of entry by which a pathogen enters the body.

The intranasal NanoVax HSV vaccine has demonstrated safety and efficacy in both prophylactic and therapeutic animal models for genital herpes. In a prophylactic guinea pig study, the intranasal vaccine prevented genital herpes infection in 92 percent of animals vaccinated. Therapeutic study animals previously infected with genital herpes who received the BlueWillow vaccine reduced recurrent lesions and viral shedding by more than 50 percent compared to animals who received no treatment.

“Genital herpes is easily and often unknowingly transmitted between partners. The lifelong infection frequently causes psychological distress and negatively impacts quality of life,” said Dr. Ali Fattom, Senior Vice President of Vaccine Research and Development, BlueWillow. “After years of research in animals, we are moving closer to studies in humans where we expect results to validate the potential of this much-needed vaccine.”

About BlueWillow

BlueWillow Biologics® is a privately-held biopharmaceutical company headquartered in Ann Arbor, Michigan, focused on developing and commercializing vaccines using its patented NanoVax® technology platform. The technology employs a novel oil-in-water nanoemulsion adjuvant that is effective when administered via intranasal or intramuscular vaccination and can elicit both mucosal and systemic immunity when applied intranasally.

BlueWillow is currently developing intranasal vaccines for several respiratory and sexually transmitted infections, including RSV, influenza, anthrax, prophylactic and therapeutic HSV-2 and chlamydia, as well as vaccines for selected allergic conditions. Visit BlueWillow.com for details on the company’s vaccine pipeline and studies completed to date.

THE MASQUE OF ANARCHY BY THE ENGLISH POET SHELLY IS AN EARLY CALL TO NONVIOLENT RESISTANCE FOLLOWING THE PETERLOO MASSACRE ON 16 August 1819 IN ENGLAND.

 

“Stand ye calm and resolute,
Like a forest close and mute,
With folded arms and looks which are
Weapons of unvanquished war.

And if then the tyrants dare,
Let them ride among you there;
Slash, and stab, and maim and hew;
What they like, that let them do.

With folded arms and steady eyes,
And little fear, and less surprise,
Look upon them as they slay,
Till their rage has died away:

Then they will return with shame,
To the place from which they came,
And the blood thus shed will speak
In hot blushes on their cheek:

Rise, like lions after slumber
In unvanquishable number!
Shake your chains to earth like dew
Which in sleep had fallen on you:

“Rise, like lions after slumber
In unvanquishable number!
Shake your chains to earth, like dew
Which in sleep had fallen on you:
Ye are many—they are few!”
Ye are many—they are few!”

 

Trump’s NLRB Members Force Adoption of New Rule Attacking Unions.

The National Labor Relation Board (NLRB) has taken a broad step towards doing away with unions in America that upsets the current collective bargaining and union recognition system. Employers can now announce a pending withdrawal of recognition within 90 days of the contract expiration and withdraw when the collective bargaining agreement ends. The Union then has 45 days to file a petition for a new election. This was a 3-1 decision based on Johnson Control’s Inc. anticipatory withdrawal of recognition to a UAW affiliate that represented 160 of its workers. (NLRB 10-CA-151843 7/3/19) In overturning portions of the 2001 ruling in Levitz Furniture, the NLRB said this ruling protected employee free choice and that it would apply the new framework retroactively. The NLRB is also considering changes to other restrictions on elections to decertify . The new decision allows the employer to cease bargaining with a union and question its majority status 90 days prior to the expiration of a contract and to unilaterally force the union to once again go through an election to prove its majority status in the workplace. This decision completely upends the union representational scheme that has brought labor peace in the workplace.

Many employees will likely loose union representation and power at the bargaining table. On the plus side, the new system will force unions into a more adversary relationship and force those unions who currently do little in the workplace between contracts to become more active in order to actually maintain majority status. But this is clearly an attack on organized labor and reflects the current lack of organization in the workplaces of America. Less than 30 percent of American workers are organized and those that are come largely from the public sector. This lack of organization by labor in the USA is what makes the governmental leaders feel free to take a stab at labor. Our response will determine weather this attack proves fatal.

War and Peace

The Trump administration has turned their
attacks on the Venezuela government into a full fledged embargo. Besides being uncalled for it is going to be no more successful then the embargo on Cuba. What it will do is cause unnecessary death and suffering by the people of Venezuela . The policy is a desperate attempt by the United States to control Venezuelan oil fields in order to ensure a steady supply of oil so that the United States can wage the war against Iraq that is being pushed by the neofascist, John Bolton, who is President Trump’s National Security advisor. Russia’s leader, Putin, famously asked John Bolton if he had removed the olive branches from the American seal. Those who advocate war lingering whether the Bolton’s or Hillary Clinton deserve the dust bins of history.

U.S. sanctions in Venezuela result in untold suffering and the death of 40’000 people

We must resist the United State’s attempts to dictate to the people of Venezuela . We have appropriated the Venezuela government ownership of Chevron Oil and other assists of their people simply because we desire complete control of their oil and other natural resources and because we refuse to let stand any government that serves its people better than we do. This is an economic and political war by United States corporate interests against the poor who struggle for a better life in their own country. The imperial desires of the United States can not be allowed to stand. Those U.S. corporate interests bring nothing but death and destruction both here and abroad.

How many die in America because we lack national health insurance? People here are dying because insulin that is $30 dollars in Canada is $300 in the United States. An Epipen that costs next ro nothing now sells for hundreds of dollars in America. Corporate interests put profit above human life.

We need to end capitalism with its exploitation at home and its wars for economic hegemony abroad .

A company called Blue Willow Biologicals has received a patent on a novel nasal vaccine that protects against Herpes Simplex 1 and 2 and has therapuetic value as well in those already infected.

The announcement by Blue Willow Bio9logicals of their novel patent for Herpes vaccine is reprinted below:

Vaccine Expected to Deliver Therapeutic and Preventive Protection

ANN ARBOR, Mich., (July 23, 2019) – BlueWillow Biologics® today announced the issuance of U.S. patent number 10,206,996 to BlueWillow for the development of an intranasal NanoVax® herpes simplex virus (HSV) vaccine. The patent protects the use of BlueWillow’s unique NanoVax adjuvant platform in the development of a vaccine that provides protection against HSV-1 and HSV-2, the two viruses that can cause genital herpes.

More than one in six people aged 14–49 are infected with genital herpes and an estimated 776,000 new infections occur annually, according to the Centers for Disease Control and Prevention (CDC). Genital herpes increases a person’s risk of contracting HIV and can lead to miscarriage and premature birth in infected pregnant women. Herpes can also be passed from the mother to child during birth, potentially resulting in neonatal herpes, a fatal infection. Most genital herpes vaccine candidates have failed or been abandoned in recent years, leaving no reliable therapeutic or preventive vaccine for the disease.

BlueWillow’s intranasal NanoVax platform elicits both mucosal and systemic immunity through its novel oil-in-water nanoemulsion (NE) adjuvant, offering a unique advantage to combat sexually transmitted infections (STIs) including genital herpes. The mucosal immunity elicited by intranasal NE vaccines provides critical protection against infections at the port of entry by which a pathogen enters the body.

The intranasal NanoVax HSV vaccine has demonstrated safety and efficacy in both prophylactic and therapeutic animal models for genital herpes. In a prophylactic guinea pig study, the intranasal vaccine prevented genital herpes infection in 92 percent of animals vaccinated. Therapeutic study animals previously infected with genital herpes who received the BlueWillow vaccine reduced recurrent lesions and viral shedding by more than 50 percent compared to animals who received no treatment.

“Genital herpes is easily and often unknowingly transmitted between partners. The lifelong infection frequently causes psychological distress and negatively impacts quality of life,” said Dr. Ali Fattom, Senior Vice President of Vaccine Research and Development, BlueWillow. “After years of research in animals, we are moving closer to studies in humans where we expect results to validate the potential of this much-needed vaccine.”

About BlueWillow

BlueWillow Biologics® is a privately-held biopharmaceutical company headquartered in Ann Arbor, Michigan, focused on developing and commercializing vaccines using its patented NanoVax® technology platform. The technology employs a novel oil-in-water nanoemulsion adjuvant that is effective when administered via intranasal or intramuscular vaccination and can elicit both mucosal and systemic immunity when applied intranasally.

BlueWillow is currently developing intranasal vaccines for several respiratory and sexually transmitted infections, including RSV, influenza, anthrax, prophylactic and therapeutic HSV-2 and chlamydia, as well as vaccines for selected allergic conditions. Visit BlueWillow.com for details on the company’s vaccine pipeline and studies completed to date.

American Lies in the Middle East

The United States is playing fast and loose with the facts regarding the Japanese ship in the Strait of Hormus on June 14. While the United States claims the ship was attacked with limpet mines, the ship captain disputes this account. The captain of the ship Courageous stated that the ship was not attacked with mines and photographs show the damage and fire were well above the water line. The ship captain believed the ship might have been hit by a flying object. In any case the U.S. claim of Iranian mine attack is patently false.

While the U.S. is looking for any excuse to go to war against Iran, this instance will not serve. The U.S. claims are rightly being denied by our allies except for Great Britain who slavishly supports any American military adventure. If the U.S. wants renewed respect in the world it must stop obvious lies. Iran has given us no reason to go to war but America has engaged in economic attacks and enforced boycotts of Iran. Enough of the lies. The time when American could make up excuses for war is long past.

Mueller Report

Many liberals and even leftists put unwarranted faith in the Mueller investigation which apart from indictments of all the President’s men disappointed on every issue regarding the President and Russian collusion. While I never had faith in Mueller given his history, temperament and and Washington establishment leanings, the reality of hiss whitewash of the President in the face of Trump’s self evident quilt is disturbing.

Apparently see no evil still prevails in Washington despite the fact that the emperor has no clothes. Most of America can see that even if Mueller is blind.

Censorship continues apace

USA Today reports that Facebook will extend its censorship to anti-vaccine news. USA Today states:

‘Facebook is considering making anti-vaccination content on its site less visible amid a measles outbreak that has reignited a conversation about preventative shots.

The social media giant that’s been criticized for spreading fake news told USA TODAY it’s “taken steps to reduce the distribution of health-related misinformation on Facebook, but we know we have more to do.”

Facebook has been fighting misinformation on its platform since the 2016 presidential election after fake accounts and news stories aimed at sowing discord among users were discovered.’